NPTX2 Polyclonal Antibody, Cy5 Conjugated
Product Specifications
Background
Long pentraxins are a family of highly conserved proteins that are expressed in the brain and central nervous system, and form multimeric complexes. Neuronal pentraxin 1 (NP1), NP2, and neuronal pentraxin receptor (NPR) are members of the long pentraxins that represent a neuronal uptake pathway that may function during synapse formation and remodeling. The NP1 gene is located on chromosome 17q25.3 and the protein product mediates the uptake of synaptic material, including the presynaptic snake venom toxin, taipoxin (3) . NP2, whose function is unknown, is located on chromosome 7q22.1 and like NP1 contains several potential N-linked glycosylation sites. NPR is expressed on the cell membrane and can form heteropentamers with NP1 and NP2 that can be released from the cell membrane by proteolysis.
Synonyms
Apexin; NARP; Neuronal pentraxin 2; Neuronal pentraxin II; Neuronal pentraxin-2; NP 2; NP-II; NP2; NPII; NPTX2; NPTX2_HUMAN.
Gene ID
P47972
Swiss Prot
4885
Cellular Locus
Secreted
Host
Rabbit
Cross Reactivity
Mouse
Immunogen
165-265/431
Target
NPTX2
Clonality
Polyclonal
Isotype
IgG
Conjugation
Cy5
Source
KLH conjugated synthetic peptide derived from human NPTX2
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
625,650nm/670nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
P47972
Predicted Cross Reactivity
Human, Rat, Dog, Cow, Sheep
Curated Selection
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