CD36 Polyclonal Antibody, AbBy Fluor™ 488 Conjugated
Product Specifications
Background
Binds to collagen, thrombospondin, anionic phospholipids and oxidized low-density lipoprotein (oxLDL) . May function as a cell adhesion molecule. Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport (By similarity) . Receptor for thombospondins, THBS1 AND THBS2, mediating their antiangiogenic effects (By similarity) . As a coreceptor for TLR4-TLR6, promotes inflammation in monocytes/macrophages. Upon ligand binding, such as oxLDL or amyloid-beta 42 binding, rapidly induces the formation of a heterodimer of TLR4 and TLR6, which is internalized and triggers inflammatory signals, leading to the NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway, as well as IL1B secretion.
Synonyms
FAT; GPIV; Scarb3; Platelet glycoprotein 4; Glycoprotein IIIb; GPIIIB; PAS IV; PAS-4; Platelet glycoprotein IV; CD36
Gene ID
12491
Swiss Prot
Q08857
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
51-150/472
Target
CD36
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 488
Source
KLH conjugated synthetic peptide derived from mouse CD36
Applications
WB, IF, Flow-Cyt
Purification
Purified by Protein A.
Excitation Emission
499nm/519nm
Concentration
Lot Dependent
Dilution
WB (WB=1:500-2000), IF (IF=1:50-200), Flow-Cyt (Flow-Cyt=1ug/Test)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
12491
Available Sizes
Curated Selection
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