RCAS1/EBAG9 Polyclonal Antibody, APC Conjugated

This gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor, which binds to the estrogen-responsive element found in the 5'-flanking region of this gene. The encoded protein is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. This gene may also participate in the suppression of cell proliferation and inducing apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE) -like proteases. Alternate splicing results in multiple transcript variants. A pseudogene of this gene has been defined on chromosome 10.

BAG9; Cancer associated surface antigen; Cancer associated surface antigen RCAS1; EB9; EBAG 9; Estrogen receptor binding fragment associated gene 9 protein; Estrogen receptor binding site associated antigen 9; PDAF; RCAS 1; RCAS1; Receptor binding cancer antigen expressed on SiSo cells.