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ANGPTL6 Polyclonal Antibody, HRP Conjugated

Product Specifications

Background

Ngptl6 (angiopoietin-like 6) is a 470 amino acid secreted protein that contains one fibrinogen C-terminal domain and is a member of the angiopoietin-like family. Expressed abundantly in liver and present at lower levels in testis, kidney, heart, brain and lung, Angptl6 plays a role in wound healing and is also thought to promote neovascularization and enhance the chemotactic activity of endothelial cells. Additionally, Angptl6 may be involved in epidermal proliferation, remodeling and regeneration and may be able to counteract expresit increment obesity by . Human Angptl6 shares 74% amino acid identity with its mouse counterpart, suggesting a conserved role between species. The gene encoding Angptl6 maps to human chromosome 19, which is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs) .

Synonyms

ARP5; AGF; Angiopoietin like 6; Angiopoietin like Protein 6; Angiopoietin related Growth Factor; Angiopoietin related protein 5; Angiopoietin-like protein 6; ; ARP5

Gene ID

83854

Swiss Prot

Q8NI99

Cellular Locus

Secreted

Host

Rabbit

Cross Reactivity

Mouse

Immunogen

371-470/470

Target

ANGPTL6

Clonality

Polyclonal

Isotype

IgG

Conjugation

HRP

Source

KLH conjugated synthetic peptide derived from human ANGPTL6

Applications

ELISA, IHC-P, IHC-F

Purification

Affinity Purified by Protein A.

Concentration

1mg/ml

Dilution

ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

83854

Predicted Cross Reactivity

Human, Rat, Sheep, Horse, Rabbit

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