SIGLEC1 Polyclonal Antibody, PE-Cy5.5 Conjugated

Product Specifications

Background

Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Preferentially binds to alpha-2,3-linked sialic acid (By similarity) . Binds to SPN/CD43 on T-cells (By similarity) . May play a role in hemopoiesis.

Synonyms

SN; CD169; SIGLEC-1; dJ1009E24.1; Sialoadhesin; Sialic acid-binding Ig-like lectin 1; SIGLEC1

Gene ID

6614

Swiss Prot

Q9BZZ2

Cellular Locus

Secreted, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Rat

Immunogen

851-950/1709

Target

SIGLEC1

Clonality

Polyclonal

Isotype

IgG

Conjugation

PE-Cy5.5

Source

KLH conjugated synthetic peptide derived from human Sialoadhesin

Applications

FCM

Purification

Purified by Protein A.

Excitation Emission

488nm/694nm

Concentration

1µg/µl

Dilution

FCM (1:20-100)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

6614

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