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Podoplanin Polyclonal Antibody

Product Specifications

Background

May be involved in cell migration and/or actin cytoskeleton organization. When expressed in keratinocytes, induces changes in cell morphology with transfected cells showing an elongated shape, numerous membrane protrusions, major reorganization of the actin cytoskeleton, increased motility and decreased cell adhesion. Required for normal lung cell proliferation and alveolus formation at birth. Induces platelet aggregation. Does not have any effect on folic acid or amino acid transport. Does not function as a water channel or as a regulator of aquaporin-type water channels.

Synonyms

T1a; Gp38; OTS-8; T1alpha; RANDAM-2; T1-alpha; Podoplanin; Aggrus; Glycoprotein 38; PA2.26 antigen; Transmembrane glycoprotein E11; Pdpn; Ots8

Swiss Prot

Q64294

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human

Immunogen

31-130/166

Target

Podoplanin

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from Rat Podoplanin

Applications

WB, ELISA

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Predicted Cross Reactivity

Mouse, Rat

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