KLF4 Polyclonal Antibody, Cy5 Conjugated

Product Specifications

Background

Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.

Synonyms

EZF; GKLF; Krueppel-like factor 4; Epithelial zinc finger protein EZF; Gut-enriched krueppel-like factor; KLF4

Gene ID

9314

Swiss Prot

O43474

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

415-513/513

Target

KLF4

Clonality

Polyclonal

Isotype

IgG

Conjugation

Cy5

Source

KLH conjugated synthetic peptide derived from human KLF4

Applications

WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

625,650nm/670nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Specificity

This antibody may crossreact with KLF2 due to high sequence similarity.

Gene ID URL

9314

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

RC219403L1 10 µg

INSIG1 (NM_198336) Human Tagged Lenti ORF Clone

Ask

View Details

FNab04252 100 µg

IL21R antibody

Ask

View Details

MBS488213-01 0.2 mg

Anti-OX40L [R4930 (Oxelumab)]

Ask

View Details

MBS488213-02 5x 0.2 mg

Anti-OX40L [R4930 (Oxelumab)]

Ask

View Details

MR222041L3 10 µg

Suco (NM_172645) Mouse Tagged Lenti ORF Clone

Ask

View Details

bsm-62026R-BF555 100 µL

NEK2 Recombinant Antibody, AbBy Fluor™ 555 Conjugated

Ask

View Details