HHV11 DNA polymerase catalytic subunit Polyclonal Antibody, AbBy Fluor™ 405 Conjugated
Product Specifications
Background
Replicates viral genomic DNA. The replication complex is composed of six viral proteins: the DNA polymerase, processivity factor, primase, primase-associated factor, helicase, and ssDNA-binding protein. Additionally, the polymerase contains an intrinsic ribonuclease H (RNase H) activity that specifically degrades RNA/DNA heteroduplexes or duplex DNA substrates in the 5' to 3' direction. Therefore, it can catalyze the excision of the RNA primers that initiate the synthesis of Okazaki fragments at a replication fork during viral DNA replication.
Synonyms
DPOL_HHV11; DNA polymerase catalytic subunit; UL30; HHV1gp046.
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Virus
Immunogen
1131-1235/1235
Target
HHV11 DNA polymerase catalytic subunit
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 405
Source
KLH conjugated synthetic peptide derived from human Human herpesvirus 1 DNA polymerase catalytic subunit
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
401nm/421nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Specificity
This antibody will detect both HHV1 and HHV2 DNA polymerase catalytic subunit
Cross Reactivity Details
HHV1
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