Anti-GITR [DTA-1]
Rat monoclonal antibody to GITR
Product Specifications
Product Name Alternative
CD357; AITR; GITR-D; Glucocorticoid-induced TNFR-related protein; TNFRSF18; Tumor necrosis factor receptor superfamily member 18
UniProt
O35714
Reactivity
Mouse
Immunogen
This antibody was raised by immunising Wistar rats with the CD25+CD4+ T cell line. Hybridoma cells were generated by fusing spleen cells from the immunized rat with P3X63Ag8.653 myeloma cells, assessed for secreting antibodies capable of neutralizing in vitro CD25+CD4+ T cell-mediated suppression of anti-CD3-stimulated T cell proliferation9, and then cloned. This DTA-1 clone secreted a monoclonal rat immunoglobulin G2a (IgG2a) that showed high neutralizing activity.
Target
GITR
Clonality
Monoclonal
Clone
DTA-1
Conjugation
Unconjugated
Field of Research
Cell Biology
Concentration
1 mg/ml
Purity
Purified
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
FC, IP, WB
Host or Source
Rat
Preservative
PBS with 0.02% Proclin 300.
Isotype
IgG2a
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