Caspase-1 p20 Polyclonal Antibody, AbBy Fluor™ 555 Conjugated

Product Specifications

Background

Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs) . Can also promote apoptosis.

Synonyms

Caspase-1; Casp1; CASP-1; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45; Casp1; Caspase-1 subunit p20; Il1bc

Gene ID

12362

Swiss Prot

P29452

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

181-280/402

Target

Caspase-1 p20

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 555

Source

KLH conjugated synthetic peptide derived from mouse Caspase-1 p20

Applications

WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

553nm/568nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

12362

Available Sizes

Curated Selection

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