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B3GALNT1 Polyclonal Antibody, RBITC Conjugated

Product Specifications

Background

This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine) . The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5) . The encoded protein of this gene does not use N-acetylglucosamine as an acceptor sugar at all. Multiple transcript variants that are alternatively spliced in the 5' UTR have been described; they all encode the same protein.

Synonyms

3-galactosyltransferase 3; 3-GalNAc-T1; 3-GalTase 3; 3-N-acetylgalactosaminyltransferase 1; 3-N-acetylgalactosaminyltransferase; b3Gal T3; b3Gal-T3; B3galnt1; B3GALT3; B3GL1_HUMAN; Beta 1,3 galactosyltransferase 3; Beta 1,3 GalTase 3; beta 1,3 N acetylgalactosaminyltransferase 1 globoside blood group; Beta 3 GalNAc T1; Beta 3 Gx T3; Beta-1; Beta-3-Gx-T3; beta3Gal T3; Beta3Gal-T3; Beta3GalT3; brainiac1; Galactosylgalactosylglucosylceramide beta D acetyl galactosaminyltransferase; Galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase; galT3; Gb4Cer; GLCT3; GLOB; Globoside synthase; globotriaosylceramide 3 beta N acetylgalactosaminyltransferase; P antibody P antigen synthase; P blood group globoside; P1 antibody UDP Gal:betaGlcNAc beta 1,3 galactosyltransferase 1; UDP Gal:betaGlcNAc beta 1,3 galactosyltransferase, polypeptide 3 Globoside blood group; UDP GalNAc:beta 1,3 N acetylgalactosaminyltransferase 1; UDP GalNAc:betaGlcNAc beta 1,3 galactosaminyltransferase, polypeptide 1 Globoside blood group; UDP N acetylgalactosamine:globotriaosylceramide beta 1,3 N acetylgalactosaminyltransferase; UDP-GalNAc:beta-1; UDP-N-acetylgalactosamine:globotriaosylceramide beta-1

Gene ID

8706

Swiss Prot

O75752

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Immunogen

231-331/331

Target

B3GALNT1

Clonality

Polyclonal

Isotype

IgG

Conjugation

RBITC

Source

KLH conjugated synthetic peptide derived from human B3GALNT1

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

570nm/595nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

8706

Predicted Cross Reactivity

Human, Mouse, Rat, Dog, Cow, Pig, Horse, Rabbit

Curated Selection

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