Isolindleyin

Isolindleyin, a butyrophenone, is a tyrosinase inhibitor, with a Kd of 54.8 μM for human tyrosinase. Isolindleyin exhibits anti-inflammatory, analgesic and anti-melanogenic activities[1].

Product Specifications

CAS Number

[87075-18-1]

UNSPSC

12352005

Target

Tyrosinase

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/isolindleyin.html

Purity

99.34

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

CC(CCC(C=C1)=CC=C1O[C@H]2[C@@H]([C@H]([C@H](O)[C@@H](CO)O2)O)OC(C3=CC(O)=C(O)C(O)=C3)=O)=O

Molecular Formula

C23H26O11

Molecular Weight

478.45

References & Citations

[1]Lee JY, et, al. Isolindleyin exerts anti-melanogenic effects in human epidermal melanocytes via direct binding to tyrosinase. Biochem Biophys Res Commun. 2021 Jan 1;534:802-807.