LXR alpha Polyclonal Antibody, APC Conjugated
Product Specifications
Background
The LXR receptors (including LXR-_ and LXR-_) bind oxysterols and play key roles in maintaining cholesterol homeostasis in macrophages, primarily by regulating multiple components of the reverse cholesterol transport. They also are potent inhibitors of inflammation and are capable of repressing cytokine and chemokine production by Toll-like receptor (TLR) -activated macrophages.
Synonyms
Oxysterols receptor LXR-beta; Liver X receptor beta; Nuclear receptor NER; Nuclear receptor subfamily 1 group H member 2; NR1H2; LXRB; NER; UNR; Liver X receptor alpha; Nuclear receptor subfamily 1 group H member 3; Oxysterols receptor LXR-alpha; NR1H3; LXRA
Gene ID
10062, 7376
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human, Rat
Immunogen
361-447/447
Target
LXR alpha
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human LXR alpha
Applications
WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
10062, 7376
Predicted Cross Reactivity
Mouse, Dog, Cow, Horse, Chicken
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