LXR alpha Polyclonal Antibody

Product Specifications

Background

The LXR receptors (including LXR-_ and LXR-_) bind oxysterols and play key roles in maintaining cholesterol homeostasis in macrophages, primarily by regulating multiple components of the reverse cholesterol transport. They also are potent inhibitors of inflammation and are capable of repressing cytokine and chemokine production by Toll-like receptor (TLR) -activated macrophages.

Synonyms

Oxysterols receptor LXR-beta; Liver X receptor beta; Nuclear receptor NER; Nuclear receptor subfamily 1 group H member 2; NR1H2; LXRB; NER; UNR; Liver X receptor alpha; Nuclear receptor subfamily 1 group H member 3; Oxysterols receptor LXR-alpha; NR1H3; LXRA

Gene ID

10062, 7376

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Rat

Immunogen

361-447/447

Target

LXR alpha

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human LXR alpha

Applications

WB, ELISA, FCM, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), FCM (1:20-100), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)