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Claudin 5 Polyclonal Antibody, HRP Conjugated

Product Specifications

Background

Plays a major role in tight junction-specific obliteration of the intercellular space.This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively, spliced __transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2008]

Synonyms

AWAL; BEC 1; BEC1; Claudin 5 (transmembrane protein deleted in velocardiofacial syndrome) ; Claudin5; Claudin-5; CLDN 5; CLDN5; CPETR L1; CPETRL 1; CPETRL1; TMDVCF; TMVCF; Transmembrane protein deleted in VCFS; Transmembrane protein deleted in velocardiofacial syndrome; Androgen withdrawal and apoptosis induced protein RVP1 like; CLD5_HUMAN.

Gene ID

7122

Swiss Prot

O00501

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse

Immunogen

29-81/218

Target

Claudin 5

Clonality

Polyclonal

Isotype

IgG

Conjugation

HRP

Source

KLH conjugated synthetic peptide derived from human Claudin 5

Applications

WB, IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (WB=1:500-2000), IHC-P (IHC-P=1:100-500), IHC-F (IHC-F=1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

7122

Predicted Cross Reactivity

Rat, Cow, Sheep, Pig, Horse, Rabbit

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