C5R1 Polyclonal Antibody, APC Conjugated
Product Specifications
Background
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520) . The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099) . Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520) .
Synonyms
C5A; C5AR; C5R1; CD88; C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin chemotactic receptor; C5a-R; C5AR1
Gene ID
728
Swiss Prot
P21730
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human
Immunogen
51-150/350
Target
C5R1
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human C5R1
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
728
Predicted Cross Reactivity
Rat, Dog, Cow, Sheep, Pig, Rabbit, GuineaPig
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15195358 1 Vial
Lentiviral mouse Ssxb6 shRNA (UAS) - Lentiviral mouse Ssxb6 shRNA (UAS, GFP) plasmid
Ask
View Details 
NEE-MY2233-1mg 1 mg
Monoclonal Anti-Influenza A virus (turkey/Germany-MV/R2472/2014) NA (H5N8) Antibody, Human IgG1 (5E5) (MALS verified)
Ask
View Details