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Nanos3 Polyclonal Antibody, Cy5.5 Conjugated

Product Specifications

Background

Plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase. Affects cell proliferation probably by repressing translation of specific mRNAs. Maintains the germ cell lineage by suppressing both Bax-dependent and -independent apoptotic pathways. Essential in the early stage embryo to protect the migrating primordial germ cells (PGCs) from apoptosis.

Synonyms

NOS3; NANOS1L; Nanos homolog 3; NOS-3; NANOS3

Gene ID

342977

Swiss Prot

P60323

Cellular Locus

Secreted, Cell membrane, Extracellular matrix

Host

Rabbit

Cross Reactivity

Mouse

Immunogen

101-173/173

Target

Nanos3

Clonality

Polyclonal

Isotype

IgG

Conjugation

Cy5.5

Source

KLH conjugated synthetic peptide derived from human Nanos3

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

675nm/694nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

342977

Predicted Cross Reactivity

Human, Rat, Cow, Sheep, Pig

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