Nanos3 Polyclonal Antibody, APC Conjugated
Product Specifications
Background
Plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase. Affects cell proliferation probably by repressing translation of specific mRNAs. Maintains the germ cell lineage by suppressing both Bax-dependent and -independent apoptotic pathways. Essential in the early stage embryo to protect the migrating primordial germ cells (PGCs) from apoptosis.
Synonyms
NOS3; NANOS1L; Nanos homolog 3; NOS-3; NANOS3
Gene ID
342977
Swiss Prot
P60323
Cellular Locus
Secreted, Cell membrane, Extracellular matrix
Host
Rabbit
Cross Reactivity
Mouse
Immunogen
101-173/173
Target
Nanos3
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human Nanos3
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
342977
Predicted Cross Reactivity
Human, Rat, Cow, Sheep, Pig
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