ZFAND5 Polyclonal Antibody, APC Conjugated
Product Specifications
Background
Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation.
Synonyms
ZA20D2; ZNF216; ZFAND5A; AN1-type zinc finger protein 5; Zinc finger A20 domain-containing protein 2; Zinc finger protein 216; ZFAND5
Gene ID
7763
Swiss Prot
O76080
Cellular Locus
Cytoplasm
Host
Rabbit
Immunogen
121-213/213
Target
ZFAND5
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human ZFAND5
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
1µg/µl
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
7763
Predicted Cross Reactivity
Human, Mouse, Rat, Cow, Sheep, Pig, Chicken, Rabbit
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Mouse Monoclonal PAGE1 Antibody (OTI3E7) [HRP]](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
![Mouse Monoclonal PEG10 Antibody (981902) [HRP]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)