Phospho-LAT (Tyr200) Polyclonal Antibody, Biotin Conjugated
Product Specifications
Background
Linker for activation of T cells (LAT) is an integral membrane protein (36 to 38 kD), which plays an important role in linking engagement of the TCR to the biochemical events of T cell activation. LAT antibody stains thymus and peripheral lymphoid tissues such as T cell areas in lymph nodes and spleen. LAT is expressed in T lymphocytes in interstitial spaces, platelets and megakaryocytes. LAT is not expressed in B cells, macrophages, plasma cells, monocytes, epithelial histiocytes and dendritic cells.
Synonyms
Linker for activation of T cell 1; 36 kDa phospho tyrosine adapter protein; LAT 1; LAT1; Linker for activation of T cells; Linker for activation of T cells family member 1; p36 38; pp36; LAT_HUMAN.
Gene ID
27040
Modification Site
Tyr200
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human
Target
Phospho-LAT (Tyr200)
Clonality
Polyclonal
Isotype
IgG
Conjugation
Biotin
Source
KLH conjugated synthetic phosphopeptide derived from human LAT around the phosphorylation site of Tyr200
Applications
ELISA, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
27040
Predicted Cross Reactivity
Mouse, Rat, Dog, Cow, Horse, Rabbit
Curated Selection
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