CXCR1 Polyclonal Antibody, Cy7 Conjugated

Product Specifications

Background

Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity.

Synonyms

C-C; CD128; CD181; CKR-1; IL8R1; IL8RA; CMKAR1; IL8RBA; CDw128a; C-C-CKR-1; C-X-C chemokine receptor type 1; CXC-R1; CXCR-1; High affinity interleukin-8 receptor A; IL-8R A; IL-8 receptor type 1; CXCR1

Gene ID

3577

Swiss Prot

P25024

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human

Immunogen

186-280/350

Target

CXCR1

Clonality

Polyclonal

Isotype

IgG

Conjugation

Cy7

Source

KLH conjugated synthetic peptide derived from human CXCR1

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

743nm/767nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

3577

Predicted Cross Reactivity

Rabbit

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CD86 (Cluster of Differentiation 86, Activation B7 2 Antigen, Activation B7-2 Antigen 3, Activation B7-2 Antigen, Activation B72 Antigen, B Lymphocyte Activation Antigen B7 2, B Lymphocyte Activation Antigen B72, B-lymphocyte Activation Antigen B7-2 2, B-lymphocyte Activation Antigen B7-2, B7 2, B7 2 Antigen, B7, B7-2, B7.2, B70, B72 Antigen, BU63, CD 86, CD28 Antigen Ligand 2 2, CD28 Antigen Ligand 2, Cd28l2, CD28LG2, CD86 Antigen (CD28 Antigen Ligand 2, B7-2 Antigen) 1, 2, CD86 Antigen (CD28 Antigen Ligand 2, B7-2 Antigen), CD86 Antigen, CD86 Molecule, CD86_HUMAN, CLS1, CTLA 4 Counter Receptor B7 2, CTLA 4 Counter Receptor B7.2, CTLA-4 Counter-receptor B7.2 2, 3, CTLA-4 Counter-receptor B7.2, CTLA4 Counter Receptor B72, Early T-cell Costimulatory Molecule 1, ETC-1, FUN 1, FUN-1, FUN1, LAB72, Ly-58, Ly58, MB7, MB7-2, Membrane Glycoprotein, T Lymphocyte Activation Antigen CD86, T-lymphocyte Activation Antigen CD86, TS/A-2)

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