CYP11A1 Polyclonal Antibody, AbBy Fluor™ 750 Conjugated
Product Specifications
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. [provided by RefSeq, Jul 2008]
Synonyms
Cholesterol 20 22 desmolase; Cholesterol desmolase; Cholesterol monooxygenase side chain cleaving; Cholesterol side chain cleavage enzyme; CYP 11A; CYP11A; CYPXIA1; Cytochrome P450 11A1; Cytochrome P450 11A1 mitochondrial; Cytochrome P450 family 11 subfamily A polypeptide 1; Cytochrome P450 subfamily XIA cholesterol side chain cleavage; Cytochrome P450 subfamily XIA; Cytochrome P450C11A1; P450scc; P450SCC; Steroid 20 22 lyase.
Gene ID
1583
Swiss Prot
P05108
Cellular Locus
Mitochondrion, Membrane bound
Host
Rabbit
Cross Reactivity
Rat
Immunogen
60-110/521
Target
CYP11A1
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 750
Source
KLH conjugated synthetic peptide derived from human CYP11A1/P450SCC
Applications
WB, IF (IHC-P)
Purification
Purified by Protein A.
Excitation Emission
749nm/775nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
1583
Curated Selection
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