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CYP11A1 Polyclonal Antibody, APC-Cy7 Conjugated

Product Specifications

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. [provided by RefSeq, Jul 2008]

Synonyms

Cholesterol 20 22 desmolase; Cholesterol desmolase; Cholesterol monooxygenase side chain cleaving; Cholesterol side chain cleavage enzyme; CYP 11A; CYP11A; CYPXIA1; Cytochrome P450 11A1; Cytochrome P450 11A1 mitochondrial; Cytochrome P450 family 11 subfamily A polypeptide 1; Cytochrome P450 subfamily XIA cholesterol side chain cleavage; Cytochrome P450 subfamily XIA; Cytochrome P450C11A1; P450scc; P450SCC; Steroid 20 22 lyase.

Gene ID

1583

Swiss Prot

P05108

Cellular Locus

Mitochondrion, Membrane bound

Host

Rabbit

Cross Reactivity

Rat

Immunogen

60-110/521

Target

CYP11A1

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC-Cy7

Source

KLH conjugated synthetic peptide derived from human CYP11A1/P450SCC

Applications

WB, IF (IHC-P)

Purification

Purified by Protein A.

Excitation Emission

650nm/780nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

1583

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