Lymphotoxin Beta Polyclonal Antibody
Product Specifications
Background
Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex and this complex is the primary ligand for the lymphotoxin-beta receptor. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is probably non-functional. Alternative splicing results in multiple transcript variants encoding different isoforms.
Synonyms
LT beta; LT-beta; LTB; lymphotoxin beta TNF superfamily, member 3; lymphotoxin beta; lymphotoxin-beta; OTTHUMP00000038214; p33; TNF C; TNF-C; TNFC; TNFC_HUMAN; TNFSF3; tumor necrosis factor C lymphotoxin beta; tumor necrosis factor C; tumor necrosis factor ligand superfamily member 3.
Gene ID
4050
Swiss Prot
Q06643
Cellular Locus
Cell membrane
Host
Rabbit
Immunogen
171-244/244
Target
Lymphotoxin Beta
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human Lymphotoxin Beta
Applications
WB, ELISA
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
4050
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Cow, Horse, Rabbit
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