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Lymphotoxin Beta Polyclonal Antibody

Product Specifications

Background

Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex and this complex is the primary ligand for the lymphotoxin-beta receptor. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is probably non-functional. Alternative splicing results in multiple transcript variants encoding different isoforms.

Synonyms

LT beta; LT-beta; LTB; lymphotoxin beta TNF superfamily, member 3; lymphotoxin beta; lymphotoxin-beta; OTTHUMP00000038214; p33; TNF C; TNF-C; TNFC; TNFC_HUMAN; TNFSF3; tumor necrosis factor C lymphotoxin beta; tumor necrosis factor C; tumor necrosis factor ligand superfamily member 3.

Gene ID

4050

Swiss Prot

Q06643

Cellular Locus

Cell membrane

Host

Rabbit

Immunogen

171-244/244

Target

Lymphotoxin Beta

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human Lymphotoxin Beta

Applications

WB, ELISA

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

4050

Predicted Cross Reactivity

Human, Mouse, Rat, Dog, Cow, Horse, Rabbit

Curated Selection

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