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Ulex Europaeus Lectin 1 Antibody, RBITC Conjugated

Product Specifications

Background

Ulex Europaeus is a European gorse shrub with fragrant golden-yellow flowers. Ulex Europaeus-I Lectin is a 46 kDa glycoprotein known to interact with -L fucosyl residues in oligosaccharides present on the membranes of human blood group O erythrocytes, human endothelial cells and a variety of human and animal epithelial cells. This antibody reacts with Ulex Europaeus Lectin 1 bound to human endothelial cells of normal and neoplastic blood and lymphatic vesicles. It also reacts with human epithelia such as in the colon, bronchus, epidermis, sweat gland ducts and hair follicles. It also reacts with for Ulex Europaeus Lectin 1 bound to vascular endothelium and squamous epithelium of human tonsil. While erythrocytes may be stained, no other tonsilar elements are reactive with the antibody. This antibody may be useful in the detection of vascular tumors, the investigation of vascular invasion by tumor cells, for determination of Ulex Europaeus Lectin 1 binding to normal, embryonal, dysplastic and neoplastic epithelial and the study of storage diseases such as fucosidosis.

Synonyms

UEA 1; UEA I; UEA-I; UEAI; UEA1; UEA-1; UEA1; Ulex europaeus agglutinin; Anti HO lectin 1; Anti HO lectin I; Anti-H (O) lectin 1.

Swiss Prot

P22972

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Plant

Immunogen

101-200/243

Target

Ulex Europaeus Lectin 1

Clonality

Polyclonal

Isotype

IgG

Conjugation

RBITC

Source

KLH conjugated synthetic peptide derived from Ulex europaeus (Furze) Anti-H (O) lectin 1

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

570nm/595nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Cross Reactivity Details

Ulex europaeus

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