CTLA4 Polyclonal Antibody, APC-Cy7 Conjugated
Product Specifications
Background
Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
Synonyms
CD; GSE; GRD4; CD152; CTLA-4; IDDM12; CELIAC3; Cytotoxic T-lymphocyte protein 4; Cytotoxic T-lymphocyte-associated antigen 4; CTLA4
Gene ID
1493
Swiss Prot
P16410
Cellular Locus
Cell membrane, Extracellular matrix
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
75-170/223
Target
CTLA4
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC-Cy7
Source
KLH conjugated synthetic peptide derived from human CTLA-4/CD152
Applications
WB, FCM, IF (IHC-P)
Purification
Purified by Protein A.
Excitation Emission
650nm/780nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
1493
Predicted Cross Reactivity
Dog, Cow, Sheep, Rabbit
Curated Selection
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