Phospho-AR/Androgen receptor (Ser578) Polyclonal Antibody
Product Specifications
Background
Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.
Synonyms
KD; AIS; TFM; DHTR; SBMA; HYSP1; NR3C4; SMAX1; HUMARA; Androgen receptor; Dihydrotestosterone receptor; Nuclear receptor subfamily 3 group C member 4; AR
Gene ID
367
Swiss Prot
P10275
Modification Site
Ser578
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
550-600/919
Target
Phospho-AR/Androgen receptor (Ser578)
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic phosphopeptide derived from human Androgen Receptor around the phosphorylation site of Ser578 [CG (p-S) CK]
Applications
WB, IHC-P, IHC-F, IF, Flow-Cyt
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500), IF (), Flow-Cyt (1ug/Test)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C for 12 months.
Specificity
This phosphorylation site is homologous to that of Ser558 in Mouse and Ser561 in Rat.
Gene ID URL
367
Curated Selection
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