LDLR Polyclonal Antibody, AbBy Fluor™ 647 Conjugated
Product Specifications
Background
Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, functions as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells.
Synonyms
FH; FHC; LDLCQ2; Low-density lipoprotein receptor; LDL receptor; LDLR
Gene ID
3949
Swiss Prot
P01130
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse
Immunogen
781-860/860
Target
LDLR
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 647
Source
KLH conjugated synthetic peptide derived from human LDL-R
Applications
WB, FCM, IF (IHC-P)
Purification
Purified by Protein A.
Excitation Emission
650nm/665nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
3949
Predicted Cross Reactivity
Rat, Dog, Cow, Pig, Horse, Rabbit, GuineaPig
Cross Reactivity Details
Hamster
Curated Selection
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