Angiopoietin 2 Polyclonal Antibody, Cy5.5 Conjugated
Product Specifications
Background
Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
Synonyms
ANG2; AGPT2; Angiopoietin-2; ANG-2; ANGPT2
Gene ID
285
Swiss Prot
O15123
Cellular Locus
Secreted
Host
Rabbit
Cross Reactivity
Human
Immunogen
401-496/496
Target
Angiopoietin 2
Clonality
Polyclonal
Isotype
IgG
Conjugation
Cy5.5
Source
KLH conjugated synthetic peptide derived from human Angiopoietin 2
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
675nm/694nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
285
Predicted Cross Reactivity
Mouse, Rat, Dog, Pig, Chicken
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
038743-ML490 100 µL
MYO19, ID (MYO19, MYOHD1, Unconventional myosin-XIX, Myosin head domain-containing protein 1) (MaxLight 490) discontinued
Ask
View Details 
CK-bio-13846-01 48 Tests
Human Tumor necrosis factor receptor superfamily member 4, Tnfrsf4/Ox40 ELISA Kit
Ask
View Details CK-bio-13846-02 96 Tests
Human Tumor necrosis factor receptor superfamily member 4, Tnfrsf4/Ox40 ELISA Kit
Ask
View Details 
CK-bio-13846-03 5x 96 Tests
Human Tumor necrosis factor receptor superfamily member 4, Tnfrsf4/Ox40 ELISA Kit
Ask
View Details