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MRP1/ABCC1 Polyclonal Antibody, PE-Cy5 Conjugated

Product Specifications

Background

Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency.

Synonyms

MRP; Mrp1; Mdrap; Abcc1a; Abcc1b; Multidrug resistance-associated protein 1; ATP-binding cassette sub-family C member 1; Leukotriene C (4) transporter; LTC4 transporter; Abcc1

Gene ID

17250

Swiss Prot

O35379

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human, Rat

Immunogen

501-600/1531

Target

MRP1/ABCC1

Clonality

Polyclonal

Isotype

IgG

Conjugation

PE-Cy5

Source

KLH conjugated synthetic peptide derived from mouse MRP1

Applications

WB, FCM

Purification

Purified by Protein A.

Excitation Emission

488nm/670nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

17250

Predicted Cross Reactivity

Mouse, Cow, Chicken

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