Growth hormone receptor Polyclonal Antibody, AbBy Fluor™ 647 Conjugated
Product Specifications
Background
Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway (By similarity) . The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. Isoform 2 up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling.
Synonyms
GHBP; Growth hormone receptor; GH receptor; Somatotropin receptor; GHR
Gene ID
2690
Swiss Prot
P10912
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
101-200/451
Target
Growth hormone receptor
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 647
Source
KLH conjugated synthetic peptide derived from human GHR
Applications
WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/665nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
2690
Predicted Cross Reactivity
Dog, Cow, Sheep, Pig, Chicken
Curated Selection
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