Connexin 43 Polyclonal Antibody, PE Conjugated

Product Specifications

Background

Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity) .

Synonyms

HSS; CMDR; CX43; GJAL; ODDD; AVSD3; HLHS1; Gap junction alpha-1 protein; Connexin-43; Gap junction 43 kDa heart protein; GJA1

Gene ID

2697

Swiss Prot

P17302

Cellular Locus

Cytoplasm, Cell membrane, Extracellular matrix

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

Connexin 43

Clonality

Polyclonal

Isotype

IgG

Conjugation

Source

KLH conjugated synthetic peptide derived from human Connexin-43

Applications

WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

496,564nm/578nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

2697

Predicted Cross Reactivity

Dog, Cow, Chicken

Curated Selection

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