Connexin 43 Polyclonal Antibody, APC-Cy7 Conjugated
Product Specifications
Background
Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity) .
Synonyms
HSS; CMDR; CX43; GJAL; ODDD; AVSD3; HLHS1; Gap junction alpha-1 protein; Connexin-43; Gap junction 43 kDa heart protein; GJA1
Gene ID
2697
Swiss Prot
P17302
Cellular Locus
Cytoplasm, Cell membrane, Extracellular matrix
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Connexin 43
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC-Cy7
Source
KLH conjugated synthetic peptide derived from human Connexin-43
Applications
WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/780nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
2697
Predicted Cross Reactivity
Dog, Cow, Chicken
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