DVL1 Polyclonal Antibody, APC Conjugated
Product Specifications
Background
Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ) .
Synonyms
DVL; DVL1L1; DVL1P1; Segment polarity protein dishevelled homolog DVL-1; Dishevelled-1; DSH homolog 1; DVL1
Gene ID
1855
Swiss Prot
O14640
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
21-100/695
Target
DVL1
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human DVL1
Applications
WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
1855
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
040350-Biotin 200 µL
PPP1R9A, ID (PPP1R9A, KIAA1222, Neurabin-1, Neurabin-I, Neural tissue-specific F-actin-binding protein I, Protein phosphatase 1 regulatory subunit 9A) (Biotin) discontinued
Ask
View Details 
MBS1452068-01 0.02 mg (E-Coli)
Recombinant Halobacterium salinarum IMP cyclohydrolase (purO)
Ask
View Details MBS1452068-02 0.1 mg (E-Coli)
Recombinant Halobacterium salinarum IMP cyclohydrolase (purO)
Ask
View Details MBS1452068-03 0.02 mg (Yeast)
Recombinant Halobacterium salinarum IMP cyclohydrolase (purO)
Ask
View Details MBS1452068-04 0.1 mg (Yeast)
Recombinant Halobacterium salinarum IMP cyclohydrolase (purO)
Ask
View Details