Integrin alpha 5 Polyclonal Antibody, PE Conjugated

Product Specifications

Background

Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

Synonyms

FNRA; CD49e; VLA5A; Integrin alpha-5; CD49 antigen-like family member E; Fibronectin receptor subunit alpha; Integrin alpha-F; VLA-5; ITGA5

Gene ID

3678

Swiss Prot

P08648

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse

Immunogen

1021-1099/1099

Target

Integrin alpha 5

Clonality

Polyclonal

Isotype

IgG

Conjugation

Source

KLH conjugated synthetic peptide derived from human ITGA5

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

496,564nm/578nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

3678

Predicted Cross Reactivity

Rat, Cow, Sheep, Pig, Horse, Rabbit

Curated Selection

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