CCR-2 Polyclonal Antibody, APC Conjugated
Product Specifications
Background
This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene. [provided by RefSeq, Mar 2009].
Synonyms
C-C Chemokine receptor 2B; C C chemokine receptor type 2; C C CKR 2; CC chemokine receptor type 2; CC CKR 2; CCCKR2; CCR 2; CCR1L; CCR2A; CCR2B; CCR5L; CD192; CD192 antigen; Chemokine C C mot receptor 2; Chemokine CC Mot Receptor 2; CKR 2; CKR2; CKR2A; CKR2B; CMKBR2; MCP 1 R; MCP1 RECEPTOR; MCP1R; Monocyte chemoattractant protein 1 receptor; Monocyte Chemotactic Protein 1 Receptor; CCR2_HUMAN; C-C chemokine receptor type 2; C-C CKR-2; CC-CKR-2; CCR-2; CCR2; Monocyte chemoattractant protein 1 receptor; MCP-1-R.
Gene ID
1231
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human
Target
CCR-2
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from mouse CCR-2
Applications
IF, Flow-Cyt
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
1µg/µl
Dilution
IF (IF=1:100-500), Flow-Cyt (Flow-Cyt=0.2μg/Test)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
1231
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6149309-01 0.1 mL
RFXAP (Regulatory Factor X Associated Protein, Regulatory Factor X-associated Protein, RFX-associated Protein, RFX DNA-binding Complex 36kD Subunit) (FITC)
Sign In for Pricing
View Details MBS6149309-02 5x 0.1 mL
RFXAP (Regulatory Factor X Associated Protein, Regulatory Factor X-associated Protein, RFX-associated Protein, RFX DNA-binding Complex 36kD Subunit) (FITC)
Sign In for Pricing
View Details 
268195-01 5 mg
1-[2-[ (3S) -3-[3-[ (1E) -2- (7-Chloro-2-quinolinyl) ethenyl]phenyl]-3-hydroxypropyl]phenyl]acetate
Sign In for Pricing
View Details