CD45 Polyclonal Antibody, AbBy Fluor™ 647 Conjugated

Product Specifications

Background

Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity) .

Synonyms

LCA; LY5; B220; CD45; L-CA; T2; CD45R; GP18; Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen; PTPRC

Gene ID

5788

Swiss Prot

P08575

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human

Immunogen

1210-1304/1304

Target

CD45

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 647

Source

KLH conjugated synthetic peptide derived from human CD45

Applications

WB, FCM, IF (IHC-P), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/665nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Specificity

The antibody is predicted to work with Mouse and Rat samples, but with decreased sensitivity compared to human samples.

Gene ID URL

5788

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NB100-58963 0.1 mg

Goat Polyclonal Kallikrein 5 Antibody

Ask

View Details

RHC44602 100 μg

Anti-Human FURIN Nanobody (SAA1044)

Ask

View Details

036608-ML550 100 µL

Histone H2B, NT (HIST1H2BB, H2BFF, HIST1H2BE, Histone H2B type 1-B, Histone H2B.1, Histone H2B.f) (MaxLight 550) discontinued

Ask

View Details

HY-176176S 1 Each

MDEKMLVLWVVALS (Gly-13C2,15N) IST

Ask

View Details

222122-01 50 µL

DDX3 (ATP-Dependent RNA Helicase DDX3X, DEAD box Protein 3, X-Chromosomal, DEAD box, X Isoform, Helicase-like Protein 2, HLP2, DDX3X, DBX, DDX3) discontinued

Ask

View Details

222122-02 100 µL

DDX3 (ATP-Dependent RNA Helicase DDX3X, DEAD box Protein 3, X-Chromosomal, DEAD box, X Isoform, Helicase-like Protein 2, HLP2, DDX3X, DBX, DDX3) discontinued

Ask

View Details