CD45 Polyclonal Antibody, APC Conjugated

Product Specifications

Background

Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity) .

Synonyms

LCA; LY5; B220; CD45; L-CA; T2; CD45R; GP18; Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen; PTPRC

Gene ID

5788

Swiss Prot

P08575

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human

Immunogen

1210-1304/1304

Target

CD45

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC

Source

KLH conjugated synthetic peptide derived from human CD45

Applications

WB, FCM, IF (IHC-P), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Specificity

The antibody is predicted to work with Mouse and Rat samples, but with decreased sensitivity compared to human samples.

Gene ID URL

5788

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

48831034 100 µg

TUBGCP2 Protein Lysate (Mouse) with C-HA Tag

Ask

View Details

TA359732 100 µL

SULT2B1 Rabbit Polyclonal Antibody

Ask

View Details

AK9162-1000 1mg

rHu CD40 Ligand

Ask

View Details