FADD Polyclonal Antibody, AbBy Fluor™ 647 Conjugated

Product Specifications

Background

Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis (By similarity) . Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling (By similarity) .

Synonyms

Mort1/FADD; FAS-associated death domain protein; FAS-associating death domain-containing protein; Mediator of receptor induced toxicity; Protein FADD; Fadd; Mort1

Gene ID

14082

Swiss Prot

Q61160

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Rat

Immunogen

1-80/205

Target

FADD

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 647

Source

KLH conjugated synthetic peptide derived from mouse FADD

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/665nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

14082

Predicted Cross Reactivity

Mouse, Pig

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

QP11344-2ug 2ug

Recombinant Human CD69 Protein, His, Insect-2ug

Ask

View Details

422338-01 100 mg

3- (1,3-Dioxo-1,3-dihydro-isoindol-2-yl) -propionyl chloride, rech grade

Ask

View Details

422338-02 250 mg

3- (1,3-Dioxo-1,3-dihydro-isoindol-2-yl) -propionyl chloride, rech grade

Ask

View Details

NBP3-06311FR 0.1 mL

Rabbit Polyclonal FAM149B1 Antibody [DyLight 680]

Ask

View Details

MBS1166655-01 0.02 mg (E-Coli)

Recombinant Streptococcus pneumoniae serotype 19F GTPase obg (obg)

Ask

View Details

MBS1166655-02 0.02 mg (Yeast)

Recombinant Streptococcus pneumoniae serotype 19F GTPase obg (obg)

Ask

View Details