TIMP-1 Polyclonal Antibody, AbBy Fluor™ 750 Conjugated
Product Specifications
Background
Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP1, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro; but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors.
Synonyms
EPA; EPO; HCI; CLGI; TIMP; Metalloproteinase inhibitor 1; Erythroid-potentiating activity; Fibroblast collagenase inhibitor; Collagenase inhibitor; Tissue inhibitor of metalloproteinases 1; TIMP-1; TIMP1
Gene ID
7076
Swiss Prot
P01033
Cellular Locus
Secreted
Host
Rabbit
Cross Reactivity
Human
Immunogen
103-207/207
Target
TIMP-1
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 750
Source
KLH conjugated synthetic peptide derived from human TIMP-1
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
749nm/775nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
7076
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15350500 1 Vial
Lentiviral human RSPO1 shRNA (UAS) - Lentiviral human RSPO1 shRNA (UAS, RFP) plasmid
Ask
View Details 
134928-ML650 100 µL
TWIST2 (Twist-related Protein 2, Class A Basic Helix-loop-helix Protein 39, bHLHa39, Dermis-expressed Protein 1, DERMO1, Dermo-1, FFDD, SETLSS) (MaxLight 650)
Ask
View Details 