Dapoxetine (hydrochloride)

Dapoxetine (LY-210448) hydrochloride is an orally active and selective serotonin reuptake inhibitor (SSRI) . Dapoxetine hydrochloride can be used for the research of premature ejaculation (PE) [1].

Product Specifications

CAS Number

[129938-20-1]

Product Name Alternative

LY-210448 (hydrochloride)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Serotonin Transporter

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Dapoxetine-hydrochloride.html

Concentration

10mM

Purity

99.96

Solubility

DMSO : ≥ 32 mg/mL|H2O : 100 mg/mL (ultrasonic)

Smiles

CN(C)[C@H](C1=CC=CC=C1)CCOC2=C3C(C=CC=C3)=CC=C2.Cl

Molecular Formula

C21H24ClNO

Molecular Weight

341.87

Precautions

H302, H315, H319, H335

References & Citations

[1]Muammer Kendirci, et al. Dapoxetine, a novel selective serotonin transport inhibitor for the treatment of premature ejaculation. Ther Clin Risk Manag. 2007 Jun;3 (2) :277-89.|[2]Rabab H Sayed, et al. Dapoxetine attenuates testosterone-induced prostatic hyperplasia in rats by the regulation of inflammatory and apoptotic proteins. Toxicol Appl Pharmacol. 2016 Nov 15;311:52-60.