IASPP Polyclonal Antibody, PE Conjugated

Product Specifications

Background

Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis.

Synonyms

RAI; RAI4; IASPP; NKIP1; RelA-associated inhibitor; Inhibitor of ASPP protein; Protein iASPP; NFkB-interacting protein 1; PPP1R13B-like protein; PPP1R13L; PPP1R13BL

Gene ID

10848

Swiss Prot

Q8WUF5

Cellular Locus

Cytoplasm, Nucleus, Extracellular matrix

Host

Rabbit

Cross Reactivity

Human, Rat

Immunogen

15-100/828

Target

IASPP

Clonality

Polyclonal

Isotype

IgG

Conjugation

Source

KLH conjugated synthetic peptide derived from human IASPP

Applications

WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

496,564nm/578nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

10848

Predicted Cross Reactivity

Mouse, Dog, Cow, Sheep, GuineaPig

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