Neurobeachin Polyclonal Antibody
Product Specifications
Background
Neurobeachin binds to type II regulatory subunits of protein kinase A and anchors/targets them to the membrane. It may anchor the kinase to cytoskeletal and/or organelle-associated proteins. Neurobeachin, is also a neuron-specific multidomain protein of 327 kDa with a high-affinity binding site for the type II regulatory subunit of protein kinase A. Neurobeachin is peripherally associated with pleomorphic tubulovesicular endomembranes near the trans sides of Golgi stacks and throughout the cell body and cell processes. It is also found in a subpopulation of synapses, where it is concentrated at the postsynaptic plasma membrane.
Synonyms
A-kinase anchor protein 550; d AKAP 550; Neurobeachin protein; Rugose protein; AKAP550; NBEA_DROME.
Gene ID
26960
Cellular Locus
Cytoplasm
Host
Rabbit
Immunogen
51-150/3548
Target
Neurobeachin
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from Fruit fly Neurobeachin
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
26960
Predicted Cross Reactivity
Fruit Fly
Cross Reactivity Details
Fruit Fly
Curated Selection
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