Estrogen receptor beta Antibody, AbBy Fluor™ 594 Conjugated

Product Specifications

Background

Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.

Synonyms

Erb; ESRB; ESTRB; NR3A2; ER-BETA; ESR-BETA; Estrogen receptor beta; Nuclear receptor subfamily 3 group A member 2; ESR2

Gene ID

2100

Swiss Prot

Q92731

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

50-100/530

Target

Estrogen receptor beta

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 594

Source

KLH conjugated synthetic peptide derived from human ER-Beta

Applications

WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

590nm/617nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

2100

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

TA812910AM 100 µL

Cytoglobin (CYGB) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI9D6]

Ask

View Details

RG228949 10 µg

TKTL1 (NM_001145934) Human Tagged ORF Clone

Ask

View Details

TP726436 50 µg

ARF4 Human Recombinant Protein

Ask

View Details

41320126-4 1 L

MOPSO Buffer 0.2M, pH 7.5

Ask

View Details

TRC-H924650-250MG 250 mg

3-Hydroxy-benzaldehyde (5-Chloro-6-oxo-1,6-dihydro-pyridazin-4-yl)-hydrazone

Ask

View Details

054178-01 10 µg

Caspase 14 (CASP14), Recombinant, Human, His-Tag

Ask

View Details