PMP22 Polyclonal Antibody, AbBy Fluor™ 350 Conjugated
Product Specifications
Background
PMP22 is a 22 kDa glycoprotein expressed in the compact myelin of the peripheral nervous system. In the peripheral nervous system, PMP 22 is produced by myelinating Schwann cells and is coexpressed with the genes for myelin basic protein (MBP) during nerve development and regeneration. Alterations in the level of this protein cause several genetic human diseases. If the protein is duplicated, patients develop Charcot Marie Tooth disease. If one copy of the gene is deleted, they suffer from the inherited tendency to pressure palsies.
Synonyms
DSS; HNPP; CMT1A; CMT1E; GAS-3; Sp110; HMSNIA; Peripheral myelin protein 22; PMP-22; Growth arrest-specific protein 3; PMP22; GAS3
Gene ID
5376
Swiss Prot
Q01453
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Mouse, Rat
Immunogen
101-160/160
Target
PMP22
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 350
Source
KLH conjugated synthetic peptide derived from human PMP-22
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
346nm/442nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
5376
Predicted Cross Reactivity
Human
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6454504-01 0.2 mL
Brd7 (Bromodomain-Containing Protein 7, 75kD bromodomain Protein, Brd7, Bp75) (FITC)
Ask
View Details 
MBS6454504-02 5x 0.2 mL
Brd7 (Bromodomain-Containing Protein 7, 75kD bromodomain Protein, Brd7, Bp75) (FITC)
Ask
View Details 
H1000-50B-ML550 100 µL
HA-1 (HLA-HA1, HMHA1, KIAA0223, Minor Histocompatibility Antigen HA-1, mHag HA-1, Minor Histocompatibility Protein HA-1) (MaxLight 550) discontinued
Ask
View Details