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SHANK1 Polyclonal Antibody, Cy7 Conjugated

Product Specifications

Background

Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction.

Synonyms

SSTRIP; SPANK-1; synamon; SH3 and multiple ankyrin repeat domains protein 1; Shank1; Somatostatin receptor-interacting protein; SSTR-interacting protein

Gene ID

50944

Swiss Prot

Q9Y566

Cellular Locus

Cell membrane

Host

Rabbit

Immunogen

101-200/2161

Target

SHANK1

Clonality

Polyclonal

Isotype

IgG

Conjugation

Cy7

Source

KLH conjugated synthetic peptide derived from human Shank1

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

743nm/767nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

50944

Predicted Cross Reactivity

Human, Mouse, Rat

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