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GHRH Polyclonal Antibody, AbBy Fluor™ 750 Conjugated

Product Specifications

Background

GHRF encoded by this gene belongs to the glucagon family and is a preproprotein that is produced in the hypothalamus. The preproprotein is cleaved to form a 44 aa factor, also called somatocrinin, that acts to stimulate growth hormone release from the pituitary. Variant receptors for somatocrinin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this gene are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism.

Synonyms

GRF; GHRF; GHRH; Somatoliberin precursor; Somatocrinin; Sermorelin; SLIB_HUMAN.

Gene ID

2691

Cellular Locus

Secreted

Host

Rabbit

Cross Reactivity

Rat

Immunogen

32-59/103

Target

GHRH

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 750

Source

KLH conjugated synthetic peptide derived from human GHRF

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

749nm/775nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

2691

Predicted Cross Reactivity

Human, Mouse, Cow, Pig

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