PDGF-B Polyclonal Antibody, AbBy Fluor™ 350 Conjugated

Product Specifications

Background

Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA (By similarity) .

Synonyms

SIS; SSV; IBGC5; PDGF2; c-sis; PDGF-2; Platelet-derived growth factor subunit B; PDGF subunit B; Platelet-derived growth factor B chain; Platelet-derived growth factor beta polypeptide; Proto-oncogene c-Sis; PDGFB

Gene ID

5155

Swiss Prot

P01127

Cellular Locus

Cytoplasm, Nucleus, Secreted

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

155-210/241

Target

PDGF-B

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 350

Source

KLH conjugated synthetic peptide derived from human PDGF-B

Applications

WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

346nm/442nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

5155

Predicted Cross Reactivity

Dog, Cow, Sheep, Horse, Rabbit

Curated Selection

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