BACE1 Polyclonal Antibody, AbBy Fluor™ 647 Conjugated
Product Specifications
Background
Responsible for the proteolytic processing of the amyloid precursor protein (APP) . Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
Synonyms
ASP2; BACE; HSPC104; Beta-secretase 1; Aspartyl protease 2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2; BACE1; KIAA1149
Gene ID
23621
Swiss Prot
P56817
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
401-501/501
Target
BACE1
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 647
Source
KLH conjugated synthetic peptide derived from human BACE1
Applications
WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/665nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
23621
Predicted Cross Reactivity
Dog, Pig, Chicken, Rabbit, GuineaPig
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
129375-ML650 100 µL
MAP2K5 (Dual Specificity Mitogen-activated Protein Kinase Kinase 5, MAP Kinase Kinase 5, MAPKK 5, MAPK/ERK Kinase 5, MEK5, MKK5, PRKMK5) (MaxLight 650)
Ask
View Details 